A Study of Histopathological Changes in Fallopian Tubes in Ectopic Pregnancy

Aim: The study was conducted with the aim of studying histopathological changes in ectopic pregnancy in the fallopian tube and correlate them with clinical history. Methodology: Fifty cases of tubal ectopic were studied retrospectively to compare the histopathological changes in the lining of fallopian tube. Routine haematoxylin and eosin stain with special stains were employed to study the sections. Ratio of ciliated to secretory cells was calculated. Associated inflammation and other pathology was also studied. Results: Out of 50 cases studied majority of ectopics were on right side and presented at less than 8 weeks of gestation. Most common age group to be affected was between 28-32 yrs. Around 28 of cases had previous history of surgeries and 14% previous ectopic or abortions. We also noted a significant degree of deciliation in the tubal lining with maximum number of cases showing deciliation in fimbrial ectopics. Significant number of cases showed association with salpingitis isthmica nodosa (22%) and inflammation was seen in three fourths of all cases. Conclusion: The study highlights the association with deciliation in tubal ectopics and also the significant association with inflammation and abdominal interventions